Substrate: DNA mismatch repair protein MSH6 (DNA repair protein)
Seq-ID: P52701 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-3372882   PSMD4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ATP binding,
protein binding		 MutSalpha complex positive regulation of helicase activity,
response to UV,
meiotic mismatch repair,
negative regulation of DNA recombination,
isotype switching,
determination of adult lifespan,
somatic hypermutation of immunoglobulin genes,
DNA damage response, signal transduction resulting in induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 14 QSTLYSFFPKSPALSDANKAS - 16964243
HTP
1.00
 - -
0.41
 --
S 14 QSTLYSFFPKSPALSDANKAS - 18669648
HTP
1.00
 - -
0.41
 --
S 41 GGRAAAAPGASPSPGGDAAWS - 16964243
HTP
 - - -
0.72
 --
S 43 RAAAAPGASPSPGGDAAWSEA - 16964243
HTP
 - - -
0.72
 --
S 79 AKNLNGGLRRSVAPAAPTSCD - 18669648
HTP
 - - -
0.55
 --
S 91 APAAPTSCDFSPGDLVWAKME - 18669648
HTP
1.00
 - PWWP
0.37
 --
S 137 VRVHVQFFDDSPTRGWVSKRL - 16565220
HTP
0.45
 - PWWP
0.38
 --
S 137 VRVHVQFFDDSPTRGWVSKRL - 18220336
HTP
0.45
 - PWWP
0.38
 --
S 137 VRVHVQFFDDSPTRGWVSKRL - 18669648
HTP
0.45
 - PWWP
0.38
 --
T 139 VHVQFFDDSPTRGWVSKRLLK - 18220336
HTP
0.19
 - PWWP
0.37
 --
S 200 RLELAVCDEPSEPEEEEEMEV - 18669648
HTP
0.30
 - -
0.68
 --
T 213 EEEEEMEVGTTYVTDKSEEDN - 18669648
HTP
0.07
 - -
0.78
 --
Y 214 EEEEMEVGTTYVTDKSEEDNE - 18669648
HTP
1.00
 - -
0.77
 --
S 219 EVGTTYVTDKSEEDNEIESEE - 18669648
HTP
1.00
 - -
0.74
 --
S 227 DKSEEDNEIESEEEVQPKTQG - 15302935
HTP
0.01
 - -
0.86
 --
S 227 DKSEEDNEIESEEEVQPKTQG - 18669648
HTP
0.01
 - -
0.86
 --
S 252 SRQIKKRRVISDSESDIGGSD - 15302935
HTP
0.02
 - -
0.67
 --
S 252 SRQIKKRRVISDSESDIGGSD - 16964243
HTP
0.02
 - -
0.67
 --
S 252 SRQIKKRRVISDSESDIGGSD - 18669648
HTP
0.02
 - -
0.67
 --
S 254 QIKKRRVISDSESDIGGSDVE - 15302935
HTP
0.25
 - -
0.67
 --
S 254 QIKKRRVISDSESDIGGSDVE - 18669648
HTP
0.25
 - -
0.67
 --
S 256 KKRRVISDSESDIGGSDVEFK - 15302935
HTP
0.17
 - -
0.68
 --
S 256 KKRRVISDSESDIGGSDVEFK - 16964243
HTP
0.17
 - -
0.68
 --
S 256 KKRRVISDSESDIGGSDVEFK - 18669648
HTP
0.17
 - -
0.68
 --
S 261 ISDSESDIGGSDVEFKPDTKE - 15302935
HTP
0.15
 - -
0.78
 --
S 261 ISDSESDIGGSDVEFKPDTKE - 18669648
HTP
0.15
 - -
0.78
 --
S 348 RAFSAPQNSESQAHVSGGGDD - 17525332
HTP
0.18
 - -
0.75
 --
S 830 RLLSKIHNVGSPLKSQNHPDS - 15302935
HTP
0.14
 - MUTSd
0.43
 2O8B 2.46%
T 924 TAFDHEKARKTGLITPKAGFD - 17081983
HTP
0.16
 - MUTSd
0.39
 2O8B 43.84%

Substrate: DNA mismatch repair protein MSH6 (DNA repair protein)
Seq-ID: P54276 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
guanine/thymine mispair binding,
chromatin binding,
ATP binding		 MutSalpha complex,
nuclear chromatin		 response to UV,
mismatch repair,
negative regulation of DNA recombination,
isotype switching,
determination of adult lifespan,
somatic hypermutation of immunoglobulin genes,
DNA damage response, signal transduction resulting in induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 261 ISDSESDIGGSDVEFKPDTKQ - 17242355
HTP
0.25
 - -
0.79
 - medium

Substrate: DNA mismatch repair protein MSH6 (DNA repair protein)
Seq-ID: ENSP00000234420 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
Molecular FunctionCellular ComponentBiological Process
ATP binding
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 137 VRVHVQFFDDSPTRGWVSKRL - 17081983
HTP
 - - PWWP
0.38
 - medium
S 219 EVGTTYVTDKSEEDNEIESEE - 17081983
HTP
 - - -
0.74
 - medium
S 227 DKSEEDNEIESEEEVQPKTQG - 17081983
HTP
 - - -
0.86
 - medium
S 252 SRQIKKRRVISDSESDIGGSD - 17081983
HTP
 - - -
0.67
 - medium
S 254 QIKKRRVISDSESDIGGSDVE - 17081983
HTP
 - - -
0.67
 - medium
S 256 KKRRVISDSESDIGGSDVEFK - 17081983
HTP
 - - -
0.68
 - medium
S 261 ISDSESDIGGSDVEFKPDTKE - 17081983
HTP
 - - -
0.78
 - medium

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